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Search for author "Zhaohua Cai"

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14 Results

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  • You have accessRestricted access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen AnalogueIn Vitro and In Vivo Analysis
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day and James W. Simpkins
    Stroke. 2002;33:2485-2491, originally published October 1, 2002
    https://doi.org/10.1161/01.STR.0000030317.43597.C8
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    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 1. Structural representation of 17β-estradiol and the novel estrogen analogue 2-adam...
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    Figure 1. Structural representation of 17β-estradiol and the novel estrogen analogue 2-adamantyl-estra-1,3,5 (10)-trien-3-ol-17-one (ZYC3).
    Show Less
  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 2. Competition binding curve of ZYC3 and E2 for human recombinant ERα and human reco...
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    Figure 2. Competition binding curve of ZYC3 and E2 for human recombinant ERα and human recombinant ERβ. No binding affinity of ZYC3 to either ERα or ERβ was indicated.
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  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 3. Concentration-response curves for E2 and ZYC3 on glutamate toxicity in HT-22 cell...
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    Figure 3. Concentration-response curves for E2 and ZYC3 on glutamate toxicity in HT-22 cells. *P<0.05 vs 17βE2 (E2) group.
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  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 4. A, Effect of E2 and ZYC3 (100 μg/kg), dissolved in corn oil, on ischemic lesion v...
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    Figure 4. A, Effect of E2 and ZYC3 (100 μg/kg), dissolved in corn oil, on ischemic lesion volume of MCAO. *P<0.05 vs OVX and ZYC3 groups. B, Effect of ZYC3 (100 μg/kg) in 30% HPβCD and E2 on ischemic lesion volume of MCAO. **P<0.05 vs OVX group.
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  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    View table
    Physiological Parameters Before, During, and After MCAO
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    Physiological Parameters Before, During, and After MCAO
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  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 5. Effects of E2 and ZYC3 on CBF. Both E2 and ZYC3 significantly increased CBF in th...
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    Figure 5. Effects of E2 and ZYC3 on CBF. Both E2 and ZYC3 significantly increased CBF in the nonischemic side during MCAO. E2 and ZYC3 significantly increased CBF in both sides within 30 minutes after reperfusion. *P<0.05 vs OVX group.
    Show Less
  • You have accessRestricted access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen AnalogueIn Vitro and In Vivo Analysis
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day and James W. Simpkins
    Stroke. 2002;33:2485-2491, originally published October 1, 2002
    https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Download PDF
  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 1. Structural representation of 17β-estradiol and the novel estrogen analogue 2-adam...
    Show More
    Figure 1. Structural representation of 17β-estradiol and the novel estrogen analogue 2-adamantyl-estra-1,3,5 (10)-trien-3-ol-17-one (ZYC3).
    Show Less
  • You have access
    Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue
    Ran Liu, Shao-Hua Yang, Evelyn Perez, Kun Don Yi, Samuel S. Wu, Kathleen Eberst, Laszlo Prokai, Katalin Prokai-Tatrai, Zu Yun Cai, Douglas F. Covey, Arthur L. Day, James W. Simpkins
    Stroke October 2002, 33 (10) 2485-2491; DOI: https://doi.org/10.1161/01.STR.0000030317.43597.C8
    Figure 2. Competition binding curve of ZYC3 and E2 for human recombinant ERα and human reco...
    Show More
    Figure 2. Competition binding curve of ZYC3 and E2 for human recombinant ERα and human recombinant ERβ. No binding affinity of ZYC3 to either ERα or ERβ was indicated.
    Show Less

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Selected Facets

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  • 1978 - 2002 (Publication date)

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  • Acute Cerebral Infarction 7
  • Animal models of human disease 7
  • Neuroprotectors 7
  • Original Contribution 7
  • Original Contributions 7
  • Original Contributions Original Contribution Original Contributions 7
  • Primary prevention 7
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  • Acute Cerebral Infarction 14
  • Animal models of human disease 14
  • Neuroprotectors 14
  • Primary prevention 14

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  • Articles 2
  • Tables & Figures 12
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