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  Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in AdultsNovelty and Significance

  Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen

  Hypertension January 2016, 67 (1) 56-62; DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.06509

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  Table 1.

  By Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He and Wei Chen

  Descriptive Data of Study Variables in Baseline and Follow-Up by Race and SexShow More

  Descriptive Data of Study Variables in Baseline and Follow-Up by Race and SexShow Less
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  Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in AdultsNovelty and Significance

  Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen

  Hypertension January 2016, 67 (1) 56-62; DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.06509

  

  Figure 1.

  By Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He and Wei Chen

  Odds ratio (OR) and 95% confidence interval (CI) of baseline body mass index (BMI), waist circumference (WC), glucose, insulin, and homeostasis model...Show More

  Odds ratio (OR) and 95% confidence interval (CI) of baseline body mass index (BMI), waist circumference (WC), glucose, insulin, and homeostasis model assessment (HOMA) for incident hypertension by race.Show Less
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  Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in AdultsNovelty and Significance

  Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen

  Hypertension January 2016, 67 (1) 56-62; DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.06509

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  Table 2.

  By Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He and Wei Chen

  Descriptive Data of Study Variables in Groups by Baseline BMI and HOMAShow More

  Descriptive Data of Study Variables in Groups by Baseline BMI and HOMAShow Less
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  Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in AdultsNovelty and Significance

  Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen

  Hypertension January 2016, 67 (1) 56-62; DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.06509

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  Table 3.

  By Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He and Wei Chen

  Association Between Follow-Up Hypertension and Baseline Insulin-Resistant Adiposity Defined by BMI and HOMA, Adjusting for Covariates in Logistic Regr...Show More

  Association Between Follow-Up Hypertension and Baseline Insulin-Resistant Adiposity Defined by BMI and HOMA, Adjusting for Covariates in Logistic Regression ModelsShow Less
• You have access

  Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in AdultsNovelty and Significance

  Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen

  Hypertension January 2016, 67 (1) 56-62; DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.06509

  

  Figure 2.

  By Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He and Wei Chen

  Standardized odds ratio (OR) and 95% confidence intervals (CI) of baseline body mass index for incident hypertension by baseline homeostasis model ass...Show More

  Standardized odds ratio (OR) and 95% confidence intervals (CI) of baseline body mass index for incident hypertension by baseline homeostasis model assessment (HOMA) quartile groups.Show Less
• You have access

  Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in AdultsNovelty and Significance

  Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen

  Hypertension January 2016, 67 (1) 56-62; DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.06509

  

  Figure 3.

  By Tao Zhang, Huijie Zhang, Shengxu Li, Ying Li, Yaozhong Liu, Camilo Fernandez, Emily Harville, Lydia Bazzano, Jiang He and Wei Chen

  Relationship between baseline body mass index (BMI) and follow-up blood pressure (BP) by low and high homeostasis model assessment (HOMA) groups.Show More

  Relationship between baseline body mass index (BMI) and follow-up blood pressure (BP) by low and high homeostasis model assessment (HOMA) groups.Show Less
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  A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective

  Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George and Dan M. Roden

  Circulation: Cardiovascular Genetics. 2012;5:91-99, originally published February 14, 2012

  https://doi.org/10.1161/CIRCGENETICS.111.960930

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  A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective

  Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden

  Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930

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  Table 1.

  Candidate Gene-Based SNP SelectionShow More

  Candidate Gene-Based SNP SelectionShow Less
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  A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective

  Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden

  Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930

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  Table 2.

  Baseline Characteristics of the Study SampleShow More

  Baseline Characteristics of the Study SampleShow Less
• You have access

  A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective

  Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden

  Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930

  

  Figure.

  Manhattan plot illustrating the genotyping results. −log10 probability values are plotted against the single-nucleotide polymorphism (SNP) chromosomal...Show More

  Manhattan plot illustrating the genotyping results. −log10 probability values are plotted against the single-nucleotide polymorphism (SNP) chromosomal location. Drug-induced long-QT syndrome (diLQTS) cases versus drug-exposed control subjects are shown in black; diLQTS cases versus population control subjects in gray. Horizontal line indicates threshold of P=0.01 for SNP replication. Arrows mark associations with P≤0.01 in both comparisons.Show Less

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