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  • A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective
    Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George and Dan M. Roden
    Circulation: Cardiovascular Genetics. 2012;5:91-99, originally published February 14, 2012
    https://doi.org/10.1161/CIRCGENETICS.111.960930
  • A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective
    Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden
    Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930
    View table
    Table 1.
    Candidate Gene-Based SNP SelectionShow More
  • A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective
    Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden
    Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930
    View table
    Table 2.
    Baseline Characteristics of the Study SampleShow More
  • A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective
    Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden
    Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930
    Figure.
    Figure.
    Manhattan plot illustrating the genotyping results. −log10 probability values are plotted against the single-nucleotide polymorphism (SNP) chromosomal...Show More
  • A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de PointesClinical Perspective
    Stefan Kääb, Dana C. Crawford, Moritz F. Sinner, Elijah R. Behr, Prince J. Kannankeril, Arthur A.M. Wilde, Connie R. Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette H. Bishopric, Robert J. Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdennasser Bardai, Isabelle C. Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, A. John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H.-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn D. Ritchie, Alfred L. George, Dan M. Roden
    Circulation: Cardiovascular Genetics February 2012, 5 (1) 91-99; DOI: https://doi.org/10.1161/CIRCGENETICS.111.960930
    View table
    Table 3.
    SNPs With Significant Associations Between diLQTS Cases to Control Subjects or Population Control SubjectsShow More
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  • Arrhythmias, clinical electrophysiology, drugs (Article Type)

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