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Search for author "Ron Simon"

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    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon and Mary P. Stenzel-Poore
    Stroke. 2004;35:2576-2581, originally published October 28, 2004
    https://doi.org/10.1161/01.STR.0000143450.04438.ae
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    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon, Mary P. Stenzel-Poore
    Stroke November 2004, 35 (11) 2576-2581; DOI: https://doi.org/10.1161/01.STR.0000143450.04438.ae
    Figure 1. Effect of LPS preconditioning on infarct size. Mice were pretreated with LPS or s...
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    Figure 1. Effect of LPS preconditioning on infarct size. Mice were pretreated with LPS or saline 48 hours before MCAO. Infarcts were assessed 48 hours after MCAO and quantified as percentage area of ischemic hemisphere. Values are mean±SEM; *P<0.05 vs saline treatment; n=12 mice per group.
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    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon, Mary P. Stenzel-Poore
    Stroke November 2004, 35 (11) 2576-2581; DOI: https://doi.org/10.1161/01.STR.0000143450.04438.ae
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    TABLE 1. Effect of LPS Preconditioning on No. of CD11b+ Cells in Ischemic Brain Tissue...
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    TABLE 1. Effect of LPS Preconditioning on No. of CD11b+ Cells in Ischemic Brain Tissue
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    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon, Mary P. Stenzel-Poore
    Stroke November 2004, 35 (11) 2576-2581; DOI: https://doi.org/10.1161/01.STR.0000143450.04438.ae
    Figure 2. Effect of LPS preconditioning on microglial activation in brain after MCAO. Activ...
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    Figure 2. Effect of LPS preconditioning on microglial activation in brain after MCAO. Activated microglia populations were quantified by flow cytometry in ischemic and nonischemic brain hemispheres (dashed line) 48 hours after MCAO in LPS-preconditioned mice. A, Representative flow cytometric plot of the ischemic hemisphere of an individual mouse. Arrow indicates activated microglia (CD45-hi and CD11b-hi) present after MCAO but diminished in LPS-preconditioned mice. B, Values are mean percentage of activated microglia of total population±SEM; *P<0.05 vs saline-treated mice; n=8 to 12 mice per group.
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    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon, Mary P. Stenzel-Poore
    Stroke November 2004, 35 (11) 2576-2581; DOI: https://doi.org/10.1161/01.STR.0000143450.04438.ae
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    TABLE 2. Effect of LPS Preconditioning on WBC Infiltration in Brain After MCAO in Mice...
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    TABLE 2. Effect of LPS Preconditioning on WBC Infiltration in Brain After MCAO in Mice
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    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon, Mary P. Stenzel-Poore
    Stroke November 2004, 35 (11) 2576-2581; DOI: https://doi.org/10.1161/01.STR.0000143450.04438.ae
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    TABLE 3. Effect of LPS Preconditioning on Circulating WBCs After MCAO
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    TABLE 3. Effect of LPS Preconditioning on Circulating WBCs After MCAO
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  • You have access
    Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice
    Holly L. Rosenzweig, Nikola S. Lessov, David C. Henshall, Manabu Minami, Roger P. Simon, Mary P. Stenzel-Poore
    Stroke November 2004, 35 (11) 2576-2581; DOI: https://doi.org/10.1161/01.STR.0000143450.04438.ae
    Figure 3. Effect of LPS preconditioning on monocyte activation in blood after MCAO. Activat...
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    Figure 3. Effect of LPS preconditioning on monocyte activation in blood after MCAO. Activated monocytes in blood were quantified by flow cytometry 48 hours after MCAO in LPS-preconditioned mice. A, Representative flow cytometric plot of blood sample from an individual mouse. Arrow indicates activated monocytes present after MCAO (CD11b-hi) but diminished in LPS-preconditioned mice. B, Values are mean percentage of activated monocytes of total monocytes±SEM. *P<0.05 vs saline-treated mice; n=8 to 12 per group. Controls: saline injection (39.3±4.3%) and LPS injection (25.3±4.3%) vs saline/MCAO; P<0.05.
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  • Acute Cerebral Infarction 7
  • Animal models of human disease 7
  • Ischemic biology - basic studies 7

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  • Articles 1
  • Tables & Figures 6
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