Circulation --

Publish Ahead of Print

These manuscripts in the Publish-Ahead-of-Print area have been accepted for publication in Circulation. They have been typeset, copyedited, and reviewed by the author, but they have not appeared in a print or online issue of the journal. In some cases, a manuscript accepted and published ahead of print may be revised before it is eventually published in print and online. In these cases, a new revised version of the manuscript will be added online, as well as its accompanying erratum.

These published-ahead-of-print manuscripts appear online as PDFs approximately 2 weeks before publication in the printed and online editions of Circulation. Each manuscript published online ahead of print is citable, with the official publication date being the date of the manuscript's first online posting. Circulation papers are assigned Digital Object Identifiers (DOIs), providing a persistent, permanent way to identify manuscripts published in the online environment.

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To see an article, click its [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

November 18, 2009

Paul A. Gurbel, Kevin P. Bliden, Kathleen Butler, Udaya S. Tantry, Tania Gesheff, Cheryl Wei, Renli Teng, Mark J. Antonino, Shankar B. Patil, Arun Karunakaran, Dean J. Kereiakes, Cordel Parris, Drew Purdy, Vance Wilson, Gary S. Ledley, and Robert F. Storey: Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease. Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Cornonary Disease: The ONSET/OFFSET Study
Circulation 2009: published online before print November 18, 2009, 10.1161/CIRCULATIONAHA.109.912550. [Abstract] [PDF] [Data Supplement]

Frederick G. Kushner, Mary Hand, Sidney C. Smith Jr, Spencer B. King III, Jeffrey L. Anderson, Elliott M. Antman, Steven R. Bailey, Eric R. Bates, James C. Blankenship, Donald E. Casey Jr, Lee A. Green, Judith S. Hochman, Alice K. Jacobs, Harlan M. Krumholz, Douglass A. Morrison, Joseph P. Ornato, David L. Pearle, Eric D. Peterson, Michael A. Sloan, Patrick L. Whitlow, and David O. Williams: 2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update). A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Circulation 2009: published online before print November 18, 2009, 10.1161/CIRCULATIONAHA.109.192663. [Abstract] [PDF]

November 17, 2009

Reginald L. Washington: Physical Education in Schools Helps Reduce Future Cardiovascular Risk
Circulation 2009: published online before print November 17, 2009, 10.1161/CIRCULATIONAHA.109.906115. [Abstract] [PDF]

Claudia Walther, Luise Gaede, Volker Adams, Götz Gelbrich, Alexander Leichtle, Sandra Erbs, Melanie Sonnabend, Kati Fikenzer, Antje Körner, Wieland Kiess, Mathias Bruegel, Joachim Thiery, and Gerhard Schuler: Effect of Increased Exercise in School Children on Physical Fitness and Endothelial Progenitor Cells. A Prospective Randomized Trial
Circulation 2009: published online before print November 17, 2009, 10.1161/CIRCULATIONAHA.109.865808. [Abstract] [PDF]

Bernard R. Chaitman, Regina M. Hardison, Dale Adler, Suzanne Gebhart, Mary Grogan, Salvador Ocampo, George Sopko, Jose A. Ramires, David Schneider, Robert L. Frye, and the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Study Group: The Bypass Angioplasty Revascularization Investigation 2 Diabetes Randomized Trial of Different Treatment Strategies in Type 2 Diabetes Mellitus With Stable Ischemic Heart Disease. Impact of Treatment Strategy on Cardiac Mortality and Myocardial Infarction
Circulation 2009: published online before print November 17, 2009, 10.1161/CIRCULATIONAHA.109.913111. [Abstract] [PDF] [Data Supplement]

Mark A. Hlatky, Derek B. Boothroyd, Kathryn A. Melsop, Laurence Kennedy, Charanjit Rihal, William J. Rogers, Lakshmi Venkitachalam, Maria M. Brooks, and for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Study Group: Economic Outcomes of Treatment Strategies for Type 2 Diabetes Mellitus and Coronary Artery Disease in the Bypass Angioplasty Revascularization Investigation 2 Diabetes Trial
Circulation 2009: published online before print November 17, 2009, 10.1161/CIRCULATIONAHA.109.912709. [Abstract] [PDF] [Data Supplement]

November 16, 2009

Rod Passman and Alan Kadish: Shouldn't Everyone Have an Implantable Cardioverter-Defibrillator?
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.907303. [Abstract] [PDF]

Haissam Abou-Saleh, Daniel Yacoub, Jean-François Théorêt, Marc-Antoine Gillis, Paul-Eduard Neagoe, Benoit Labarthe, Pierre Théroux, Martin G. Sirois, Maryam Tabrizian, Eric Thorin, and Yahye Merhi: Endothelial Progenitor Cells Bind and Inhibit Platelet Function and Thrombus Formation
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.894642. [Abstract] [PDF] [Data Supplement]

Emanuele Di Angelantonio, Rajiv Chowdhury, Nadeem Sarwar, Kausik K. Ray, Reeta Gobin, Danish Saleheen, Alexander Thompson, Vilmundur Gudnason, Naveed Sattar, and John Danesh: B-Type Natriuretic Peptides and Cardiovascular Risk. Systematic Review and Meta-Analysis of 40 Prospective Studies
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.884866. [Abstract] [PDF] [Data Supplement]

Angela Migliorini, Renato Valenti, Rossella Marcucci, Guido Parodi, Gabriele Giuliani, Piergiovanni Buonamici, Giampaolo Cerisano, Nazario Carrabba, Gian Franco Gensini, Rosanna Abbate, and David Antoniucci: High Residual Platelet Reactivity After Clopidogrel Loading and Long-Term Clinical Outcome After Drug-Eluting Stenting for Unprotected Left Main Coronary Disease
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.883454. [Abstract] [PDF]

Stuart Watkins, Ross McGeoch, Jonathan Lyne, Tracey Steedman, Richard Good, Mairi-Jean McLaughlin, Tony Cunningham, Vladimir Bezlyak, Ian Ford, Henry J. Dargie, and Keith G. Oldroyd: Validation of Magnetic Resonance Myocardial Perfusion Imaging With Fractional Flow Reserve for the Detection of Significant Coronary Heart Disease
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.872358. [Abstract] [PDF]

Min-Seok Kim, Choon-Soo Lee, Jin Hur, Hyun-Jai Cho, Soo-In Jun, Tae-Youn Kim, Sae-Won Lee, Jung-Won Suh, Kyung-Woo Park, Hae-Young Lee, Hyun-Jae Kang, Dong-Soo Lee, Gou-Young Koh, Hironori Nakagami, Ryuichi Morishita, Young-Bae Park, and Hyo-Soo Kim: Priming With Angiopoietin-1 Augments the Vasculogenic Potential of the Peripheral Blood Stem Cells Mobilized With Granulocyte Colony-Stimulating Factor Through a Novel Tie2/Ets-1 Pathway
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.856815. [Abstract] [PDF] [Data Supplement]

Douglas L. Packer, Jordan M. Prutkin, Anne S. Hellkamp, L. Brent Mitchell, Robert C. Bernstein, Freda Wood, John P. Boehmer, Mark D. Carlson, Robert P. Frantz, Steve E. McNulty, Joseph G. Rogers, Jill Anderson, George W. Johnson, Mary Norine Walsh, Jeanne E. Poole, Daniel B. Mark, Kerry L. Lee, and Gust H. Bardy: Impact of Implantable Cardioverter-Defibrillator, Amiodarone, and Placebo on the Mode of Death in Stable Patients With Heart Failure. Analysis From the Sudden Cardiac Death in Heart Failure Trial
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.853689. [Abstract] [PDF]

John J.V. McMurray, John Kjekshus, Lars Gullestad, Peter Dunselman, Åke Hjalmarson, Hans Wedel, Magnus Lindberg, Finn Waagstein, Peer Grande, Jaromir Hradec, Gabriel Kamensk $y$ , Jerzy Korewicki, Timo Kuusi, François Mach, Naresh Ranjith, John Wikstrand, and for the CORONA Study Group: Effects of Statin Therapy According to Plasma High-Sensitivity C-Reactive Protein Concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). A Retrospective Analysis
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.109.849117. [Abstract] [PDF] [Data Supplement]

Xinli Hu, Xin Xu, Guangshuo Zhu, Dorothee Atzler, Masumi Kimoto, Ju Chen, Edzard Schwedhelm, Nicole Lüneburg, Rainer H. Böger, Ping Zhang, and Yingjie Chen: Vascular Endothelial-Specific Dimethylarginine Dimethylaminohydrolase-1–Deficient Mice Reveal That Vascular Endothelium Plays an Important Role in Removing Asymmetric Dimethylarginine
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.108.819912. [Abstract] [PDF] [Data Supplement]

Rory Hachamovitch, Xingping Kang, Aman M. Amanullah, Aiden Abidov, Sean W. Hayes, John D. Friedman, Ishac Cohen, Louise E.J. Thomson, Guido Germano, and Daniel S. Berman: Prognostic Implications of Myocardial Perfusion Single-Photon Emission Computed Tomography in the Elderly
Circulation 2009: published online before print November 16, 2009, 10.1161/CIRCULATIONAHA.108.817387. [Abstract] [PDF]

November 9, 2009

Artur Evangelista and Kim A. Eagle: Is the Optimal Management of Acute Type A Aortic Intramural Hematoma Evolving?
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.907246. [Abstract] [PDF]

Todd S. Perlstein and Mark A. Creager: The Ankle-Brachial Index as a Biomarker of Cardiovascular Risk. It's Not Just About the Legs
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.907238. [Abstract] [PDF]

John Danesh and Mark B. Pepys: C-Reactive Protein and Coronary Disease. Is There a Causal Link?
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.907212. [Abstract] [PDF]

Kimberlee M. Fischer, Christopher T. Cottage, Weitao Wu, Shabana Din, Natalie A. Gude, Daniele Avitabile, Pearl Quijada, Brett L. Collins, Jenna Fransioli, and Mark A. Sussman: Enhancement of Myocardial Regeneration Through Genetic Engineering of Cardiac Progenitor Cells Expressing Pim-1 Kinase
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.884403. [Abstract] [PDF] [Data Supplement]

Jae-Kwan Song, Ji Hye Yim, Jung-Min Ahn, Dae-Hee Kim, Joon-Won Kang, Taek Yeon Lee, Jong-Min Song, Suk Jung Choo, Duk-Hyun Kang, Cheol Hyun Chung, Jae Won Lee, and Tae-Hwan Lim: Outcomes of Patients With Acute Type A Aortic Intramural Hematoma
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.879783. [Abstract] [PDF]

Christopher Newton-Cheh, Nancy R. Cook, Martin VanDenburgh, Eric B. Rimm, Paul M. Ridker, and Christine M. Albert: A Common Variant at 9p21 Is Associated With Sudden and Arrhythmic Cardiac Death
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.879049. [Abstract] [PDF] [Data Supplement]

Tomonari Koike, Shuji Kitajima, Ying Yu, Kazutoshi Nishijima, Jifeng Zhang, Yukio Ozaki, Masatoshi Morimoto, Teruo Watanabe, Sucharit Bhakdi, Yujiro Asada, Y. Eugene Chen, and Jianglin Fan: Human C-Reactive Protein Does Not Promote Atherosclerosis in Transgenic Rabbits
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.872796. [Abstract] [PDF] [Data Supplement]

Anna C. Calkin, Brian G. Drew, Akiko Ono, Stephen J. Duffy, Michelle V. Gordon, Simone M. Schoenwaelder, Dmitri Sviridov, Mark E. Cooper, Bronwyn A. Kingwell, and Shaun P. Jackson: Reconstituted High-Density Lipoprotein Attenuates Platelet Function in Individuals With Type 2 Diabetes Mellitus by Promoting Cholesterol Efflux
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.870709. [Abstract] [PDF] [Data Supplement]

Curt Diehm, Jens Rainer Allenberg, David Pittrow, Matthias Mahn, Gerhart Tepohl, Roman L. Haberl, Harald Darius, Ina Burghaus, Hans Joachim Trampisch, and for the German Epidemiological Trial on Ankle Brachial Index Study Group: Mortality and Vascular Morbidity in Older Adults With Asymptomatic Versus Symptomatic Peripheral Artery Disease
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.865600. [Abstract] [PDF] [Data Supplement]

Benjamin Y.C. Cheong, Raja Muthupillai, James M. Wilson, Angela Sung, Steffen Huber, Samir Amin, MacArthur A. Elayda, Vei-Vei Lee, and Scott D. Flamm: Prognostic Significance of Delayed-Enhancement Magnetic Resonance Imaging. Survival of 857 Patients With and Without Left Ventricular Dysfunction
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.109.852517. [Abstract] [PDF]

Mastaneh Ahmadi-Kashani, David J. Kessler, John Day, T. Jared Bunch, Kira Q. Stolen, Scott Brown, Salam Sbaity, Brian Olshansky, and on behalf of the INTRINSIC RV Study Investigators: Heart Rate Predicts Outcomes in an Implantable Cardioverter-Defibrillator Population
Circulation 2009: published online before print November 9, 2009, 10.1161/CIRCULATIONAHA.108.847608. [Abstract] [PDF]

November 2, 2009

Lee A. Fleisher, Joshua A. Beckman, Kenneth A. Brown, Hugh Calkins, Elliot L. Chaikof, Kirsten E. Fleischmann, William K. Freeman, James B. Froehlich, Edward K. Kasper, Judy R. Kersten, Barbara Riegel, and John F. Robb: 2009 ACCF/AHA Focused Update on Perioperative Beta Blockade Incorporated Into the ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Circulation 2009: published online before print November 2, 2009, 10.1161/CIRCULATIONAHA.109.192690. [Abstract] [PDF]

Kirsten E. Fleischmann, Joshua A. Beckman, Christopher E. Buller, Hugh Calkins, Lee A. Fleisher, William K. Freeman, James B. Froehlich, Edward K. Kasper, Judy R. Kersten, John F. Robb, and R. James Valentine: 2009 ACCF/AHA Focused Update on Perioperative Beta Blockade. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Circulation 2009: published online before print November 2, 2009, 10.1161/CIRCULATIONAHA.109.192689. [Abstract] [PDF]

August 3, 2009

Laura Calabresi, Damiano Baldassarre, Samuela Castelnuovo, Paola Conca, Letizia Bocchi, Chiara Candini, Beatrice Frigerio, Mauro Amato, Cesare R. Sirtori, Paola Alessandrini, Marcello Arca, Giuliano Boscutti, Luigi Cattin, Loreto Gesualdo, Tiziana Sampietro, Gaetano Vaudo, Fabrizio Veglia, Sebastiano Calandra, and Guido Franceschini: Functional Lecithin: Cholesterol Acyltransferase Is Not Required for Efficient Atheroprotection in Humans
Circulation 2009: published online before print August 3, 2009, 10.1161/CIRCULATIONAHA.108.848143. [Abstract] [PDF]