Table 3.

Associations Between Anthocyanin Intake and Risk of Myocardial Infarction Across Strata of Risk Factors for Participants From the Nurses’ Health Study II

Risk factorCases nPerson-yearsQuartile 5 vs 1P for TrendP for Interaction
Age, y
 <553501 540 4440.71 (0.50–1.03)0.16
 ≥5555110 8070.49 (0.22–1.12)0.070.42
BMI, kg/m2
 <25123823 9650.60 (0.33–1.09)0.10
 ≥25282827 2870.73 (0.49–1.09)0.200.60
Smoking
 Never1731 010 8300.53 (0.31–0.92)0.04
 Past91375 1190.99 (0.51–1.91)0.91
 Current141265 3020.75 (0.42–1.34)0.470.73
Physical activity
 Less than median259825 3740.72 (0.47–1.11)0.19
 More than median146825 8770.63 (0.36–1.08)0.120.68
Alcohol
 Nondrinker204668 9440.75 (0.46–1.25)0.61
 Drinker201982 3070.60 (0.38–0.94)0.030.26
Prevalent hypertension
 No2311 398 6920.76 (0.49–1.18)0.33
 Yes174252 5600.59 (0.35–1.00)0.050.53
History of diabetes mellitus
 No3361 609 3420.65 (0.45–0.95)0.04
 Yes6941 9100.80 (0.34–1.86)0.770.57
  • Multivariate model adjusted for age, physical activity, smoking, body mass index (BMI), alcohol, energy, menopausal status, postmenopausal hormone use, aspirin use, oral contraceptive use, family history of myocardial infarction, cereal fiber, saturated fatty acids, trans fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, and caffeine.