Table 4.

Association of Excess Weight Gain With Treatment in the DCCT and Presence of Coronary Artery Calcium Accumulation (Score >6.25) in EDIC (n = 925)

VariableOdds Ratio95% CIP Value
Excessive gainers vs minimal gainers1.550.97 to 2.490.07
Intensive vs Conventional Therapy0.980.68 to 1.420.94
Sex (Female vs Male)0.340.24 to 0.50<0.001
Age1.131.10 to 1.17<0.001
Hemoglobin A1c1.251.06 to 1.490.01
Albumin Excretion Rate1.0011.000 to 1.0020.27
Diastolic BP0.970.93 to 1.020.26
Systolic BP1.0240.99 to 1.060.11
Smoking (yes/no)2.191.43 to 3.36<0.001
CT scanner type1.000.97 to 1.020.86
  • Multiple logistic regression analysis. See text for definition of excessive gainers and minimal gainers. Covariables are weighted means. BP indicates blood pressure; CI, confidence interval; CT, computed tomography; DCCT, Diabetes Control and Complications Trial; and EDIC, Epidemiology of Diabetes Interventions and Complications study.