Table 3.

Association of Excess Weight Gain With Treatment in the DCCT and Carotid Intima Media Thickness Measured at EDIC Year 6 (n = 1015)

VariableRegression CoefficientStandard ErrorP Value
Excessive gainers vs non-gainers0.02870.0100.006
Intensive vs conventional therapy–0.02320.00820.005
Sex (female vs male)–0.0320.0076<0.001
Age0.00680.00063<0.001
Hemoglobin A1c–0.0008650.003580.81
Albumin excretion rate0.00000240.000001870.19
Diastolic BP–0.002680.0001020.009
Systolic BP0.00420.00065<0.001
Smoking (yes/no)0.0340.0096<0.001
Site of machine measurement0.000720.000500.14
  • Multiple linear regression analysis. See text for definition of excessive gainers and minimal gainers. Covariables are weighted means. BP indicates blood pressure; DCCT, Diabetes Control and Complications Trial; and EDIC, Epidemiology of Diabetes Interventions and Complications study.

  • Bonferoni significance threshold, P = 0.025.