Table 2.

Association of Excess Weight Gain With Treatment in the DCCT and Carotid Intima Media Thickness Measured at EDIC Year 1 (n = 1015)

VariableRegression CoefficientStandard ErrorP Value*
Excessive gainers vs minimal gainers0.0250.0073<0.001
Intensive vs conventional therapy–0.00740.00630.25
Sex (female vs male)–0.0260.0053<0.002
Age0.00520.00043<0.001
Hemoglobin A1c0.00150.00250.56
Albumin excretion rate0.00000800.0000190.68
Diastolic BP–0.002780.00072<0.001
Systolic BP0.00350.00048<0.001
Smoking (yes/no)0.00880.00630.16
Site of machine measurement–0.00160.00035<0.001
  • Multiple linear regression analysis. See text for definition of excessive gainers and minimal gainers. Covariables are weighted means. BP indicates blood pressure; DCCT, Diabetes Control and Complications Trial; and EDIC, Epidemiology of Diabetes Interventions and Complications study.

  • * Bonferoni significance threshold, P = 0.025.