Table 4.

Distribution of the Changes in Serum Creatinine and Cystatin C Levels in the 2 Groups

Control Group (n=146)RenalGuard Group (n=146)P
Changes in creatinine at 48 hours
    Absolute difference from baseline, mg/dL0.14±0.46−0.05±0.32<0.001
    Increase ≥25%, n (%)19 (13)4 (2.7)
    Increase ≥50%, n (%)11 (7.5)1 (0.7)
    Increase ≥0.5 mg/dL, n (%)22 (15)9 (6)
Changes in cystatin C at 24 h*
    Absolute difference from baseline, mg/dL0.02±0.32−0.08±0.260.002
    Increase ≥0.3 mg/dL, n (%)21 (15.5)11 (8.5)
    Increase ≥10%, n (%)33 (24)22 (16)
    Increase ≥15%, n (%)23 (17)17 (12)
    Increase ≥25%, n (%)14 (10)5 (3.5)
Changes in cystatin C a 48 h*
    Absolute difference from baseline, mg/dL0.12±0.42−0.0±0.30.001
    Increase ≥0.3 mg/dL, n (%)29 (21)16 (12)
    Increase ≥10%, n (%)47 (34)29 (22)
    Increase ≥15%, n (%)35 (25.5)21 (16)
    Increase ≥25%, n (%)23 (17)11 (8.5)
  • * Serum cystatin C values were available in 137 patients in each group.