Table 56135.

Pharmacological Treatment Before Cardioversion in Patients With Persistent Atrial Fibrillation: Effects of Various Antiarrhythmic Drugs on Acute and Subacute Outcome of Transthoracic Direct Current Shock

Enhance Conversion by DC Shock and Prevent IRAF*Suppress SRAF and Maintenance Therapy ClassRecommendation ClassLevel of Evidence
All drugs (except beta-blockers and amiodarone) should be initiated in hospital. IRAF indicates immediate recurrence of atrial fibrillation; SRAF, subacute recurrence of atrial fibrillation; and DC, direct current.
*Drugs are listed alphabetically within each class of recommendation.
EffectiveAmiodaroneAll drugs in recommendation Class I (except ibutilide) plus beta-blockersIB
Flecainide
Ibutilide
Propafenone
Propafenone+verapamil
Quinidine
Sotalol
Uncertain/unknownBeta-blockers DiltiazemIIbB
DisopyramideDofetilide
DiltiazemVerapamil
Dofetilide
Procainamide
Verapamil