Table 96135.

Published Risk-Stratification Schemes for Primary* Prevention of Thromboembolism in Patients With Nonvalvular Atrial Fibrillation

SourceHigh RiskIntermediate RiskLow Risk
BP indicates blood pressure. Patients are classified on the basis of the presence or absence of any risk factor.
Adapted with permission from Am J Med, Vol. 109, Pearce et al., Assessment of these schemes for stratifying stroke risk in patients with nonvalvular atrial fibrillation, pp. 45–51, © 2000, with permission, from Excerpta Medica, Inc. (195).
*Patients with AF and prior thromboembolism are at high risk of stroke, and anticoagulation is indicated for secondary prevention in such cases.
†Did not distinguish high-risk from intermediate-risk patients.
‡Left ventricular dysfunction refers to moderate to severe wall motion abnormality assessed globally by 2-dimensional echocardiography, reduced ejection fraction, fractional shortening less than 0.25 by M-mode echocardiography, or clinical heart failure.
Atrial Fibrillation Investigators (194)Age greater than or equal to 65 yearsAge less than 65 years No high-risk features
History of hypertensionNo high-risk features
Coronary artery disease
Diabetes
American College of Chest Physicians (193)Age greater than 75 yearsAge 65–75 yearsAge less than 65 years
History of hypertensionDiabetesNo risk factors
Left ventricular dysfunctionCoronary artery disease
More than 1 intermediate risk factorThyrotoxicosis
Stroke Prevention in Atrial Fibrillation (186)Women greater than 75 yearsHistory of hypertensionNo high-risk features
Systolic BP greater than 160 mm HgNo high-risk featuresNo history of hypertension
Left ventricular dysfunction