Table 2.

Medications to Maintain Cardiac Output and for Postresuscitation Stabilization

MedicationDose RangeComment
Inamrinone0.75–1 mg/kg IV/IO over 5 minutes; may repeat × 2 then: 5–10 mcg/kg per minuteInodilator
Dobutamine2–20 mcg/kg per minute IV/IOInotrope; vasodilator
Dopamine2–20 mcg/kg per minute IV/IOInotrope; chronotrope; renal and splanchnic vasodilator in low doses; pressor in high doses
Epinephrine0.1–1 mcg/kg per minute IV/IOInotrope; chronotrope; vasodilator in low doses; pressor in higher doses
MilrinoneLoading dose: 50 mcg/kg IV/IO over 10–60 min then 0.25–0.75 mcg/kg per minuteInodilator
Norepinephrine0.1–2 mcg/kg per minuteVasopressor
Sodium nitroprussideInitial: 0.5–1 mcg/kg per minute; titrate to effect up to 8 mcg/kg per minuteVasodilator Prepare only in D5W
  • IV indicates intravenous; and IO, intraosseous.

  • Alternative formula for verifying dose during continuous infusion:

  • Infusion rate Formula