Resolving Thromboinflammation in the Brain After Ischemic Stroke?
Thromboinflammation is an integral component of ischemic stroke pathophysiology. Thrombotic and inflammatory processes are highly intertwined factors leading to cerebral vessel occlusion and stroke, which itself in turn elicits local and systemic inflammatory responses.1 Over the past decade, much insight - mainly from animal models - has been gained into basic mechanisms contributing to stroke or underlying ischemic brain damage. As a number of these might be new candidate targets to treat cerebral injury after stroke, a résumé is given in Figure 1.
- Received April 29, 2016.
- Accepted April 29, 2016.