Residual Pulmonary Hypertension After Pulmonary Endarterectomy: The Fog is Clearing
Surgical pulmonary endarterectomy (PEA) is unanimously considered the preferred treatment for chronic thromboembolic pulmonary hypertension (CTEPH),1-4 even though there has never been a randomized, controlled study evaluating the safety and efficacy of this approach. This is readily explained by the fact that CTEPH is often a rapidly fatal disease if left untreated.5, 6 PEA was developed in the early seventies of the past century7 and it remained the only treatment for CTEPH for nearly 40 years. In several countries, centers of expertise emerged and the results of surgery improved constantly. At the University of California, San Diego, the postoperative mortality in the first 143 patients who underwent PEA surgery between 1970 and 1998 was 16.8%.8 This figure dropped to 2.2% in the 500 patients operated between October 2006 and December 2010.8
- chronic thromboembolic pulmonary hypertension
- pulmonary endarterectomy
- pulmonary hypertension
- Received April 3, 2016.
- Accepted April 5, 2016.