Wild Type Transthyretin Amyloid Cardiomyopathy: A Missed Etiology of HFpEF with Evolving Treatment Implications
Heart failure is a devastating but heterogeneous disease. While ischemic heart disease and hypertension account for a significant portion of heart failure, the precise etiology and pathophysiology for many other forms of heart failure is less clear. This is particularly underscored by our repeated failed attempts to identify effective treatments for heart failure with preserved ejection fraction (HFpEF). It is only through accurate etiological diagnoses and understanding of the causes of heart failure, in particular HFpEF, associated with high mortality, that we can offer more precisely targeted therapies in the future1.
- heart failure with preserved EF
- heart failure
- Received December 5, 2015.
- Accepted December 8, 2015.