"Dans les champs de l'observation le hasard ne favorise que les esprits préparés." In the fields of observation, chance favors the prepared mind
- Louis Pasteur
What are microbleeds and what causes them?
New technological advances offer an opportunity to clarify details of human pathology and pathophysiology. The advent of T2*-weighted gradient -recalled echo (GRE) MRI imaging allowed recognition of a relatively new finding- brain "microbleeds." These lesions are very small (most often 2-5mm in diameter) round hypointense foci that were not evident on other standard MRI sequences. Susceptibility-weighted images are probably even more reliable than T2* weighted GRE images for showing these microbleeds.1 Hemosiderin within these small foci are mostly responsible for producing the alteration in magnetic resonance that allows recognition of microbleeds.
- cerebral amyloid angiopathy
- magnetic resonance imaging
- Alzheimer's disease
- Received June 22, 2015.
- Revision received June 30, 2015.
- Accepted June 30, 2015.