High Prevalence but Uncertain Clinical Significance of Orthostatic Hypotension Without Symptoms
Orthostatic hypotension (OH) is common in adults, and when accompanied by symptoms (dizziness, light-headedness, or fainting) carries an increased risk of falls, fractures, and mortality.1 Symptoms are attributed to transiently reduced cerebral perfusion. The underlying causes of OH are numerous and include dehydration, "autonomic dysfunction", and medications that affect vascular compliance or responsiveness to autonomic reflexes.2 Risk factors for OH in population-based studies include age, hypertension, hypertension treatment, diabetes, and sedative/hypnotic medication use.3
- Received October 2, 2014.
- Accepted September 30, 2014.