The Prevalence of Microvascular Dysfunction, Its Role Among Men, and Links with Adverse Outcomes: Non-Invasive Imaging Reveals the Tip of the Iceberg
Considerable evidence has accumulated to counter older concepts of a categorical definition of ischemic heart disease (IHD) as simply the presence or absence of a flow-limiting stenosis. Revised concepts increasingly recognize IHD as a continuous spectrum that is not limited to obstructive plaque seen by angiography in an epicardial coronary artery. Included in this spectrum are functional disorders of the large and smaller coronary blood vessels. These smaller vessels, collectively the coronary microcirculation, comprise most of the coronary blood vessels and control the volume and distribution of blood flow to myocardium.
- coronary microvascular function
- coronary flow reserve
- corrected TIMI frame count
- ischemic heart disease
- Received April 22, 2014.
- Accepted April 28, 2014.