Are We Moving Towards Concordance on the Principle that Lipid Discordance Matters?
In this issue of Circulation, Samia Mora, Julie Buring, and Paul Ridker publish an elegant and clinically-relevant analysis examining discordance of low-density lipoprotein cholesterol (LDL-C) with related laboratory measures and the risk implications.1 The manuscript should attract attention from a diverse set of contingents, such as those based in preventive cardiology, clinical lipidology, and laboratory medicine, to name just a few. The paper addresses the underappreciated concept of discordance between different lipid and lipoprotein measures in individual patients. The investigators address the prevalence of such discordance and its association with long-term incidence of coronary events.
- Received November 25, 2013.
- Accepted December 12, 2013.