Surgical Myectomy for Hypertrophic Obstructive Cardiomyopathy: The Cut That Heals
Hypertrophic cardiomyopathy (HCM) has been one of the most interesting and controversial disorders in cardiovascular medicine. Although initial descriptions of the pathology of hypertrophic cardiomyopathy (HCM) were published over a century ago, it was not until the surgical and pathological observations of Brock and Teare respectively that this cardiac entity came to attention in the modern era. HCM is a primary disorder of the myocardium characterized by myocyte hypertrophy and fibre disarray, myocardial fibrosis, and abnormal coronary intramural microvasculature. Although HCM is characterized by tremendous diversity in terms of phenotypic expression, genetic substrate, and clinical presentation, left ventricular outflow tract (LVOT) obstruction is an integral component of the disease, occurring in up to 70% of patients either at rest or with provocation1.
- Received June 10, 2013.
- Accepted June 12, 2013.