Valve in Valve: Another Milestone for Transcatheter Valve Therapy
The first mechanical heart valve prosthesis designed by Dr Charles Hufnagel was implanted to the descending aorta of a 30 year old woman with severe aortic regurgitation in 19521. Eight years after the initial succesful prosthetic valve implantation, Dr Harken sutured a prosthetic valve (Starr Edwards Valve) to the aortic anulus after removing the diseased native valve. During the ensuing years different types of valves made from pyrolytic carbon were tried. Though successfully remedied the aortic valve disease, mechanical prosthesis required lifelong anticoagulation resulting in high rates of bleeding and thrombosis complications.
- aortic stenosis
- transcatheter aortic valve
- transcatheter aortic valve implantation
- Received August 28, 2012.
- Accepted August 30, 2012.
- Copyright © 2012, American Heart Association, Inc. All rights reserved. Unauthorized use prohibited