Post Cardiac-Arrest Mortality is Declining: A Study of the U.S. National Inpatient Sample 2001-2009
Background—Despite several advances in post-resuscitation care over the past decade, population-based mortality rates for patients hospitalized with cardiac arrest in the United States (U.S.) have not been studied over this time period. The aim of this study was to determine the annual in-hospital mortality rates of patients with cardiac arrest from 2001-2009.
Methods and Results—The U.S. mortality rates for hospitalized patients with cardiac arrest were determined using the 2001-2009 U.S. National Inpatient Sample (NIS), a national hospital discharge database. Using the International Classification of Diseases, 9th Revision code 427.5, we identified patients hospitalized in the U.S. with cardiac arrest from 2001-2009. The main outcome measure was in-hospital mortality. A total of 1,190,860 patients were hospitalized with a diagnosis of cardiac arrest in the U.S. from 2001-2009. The in-hospital mortality rate decreased each year from 69.6% in 2001 to 57.8% in 2009. In multivariable analyses, when controlling for age, gender, race, and co-morbidities, earlier year was a strong independent predictor of in-hospital death. The mortality rate declined across all analyzed subgroups, including gender, age, race, and stratification by comorbidity.
Conclusions—The in-hospital mortality rate of patients hospitalized with cardiac arrest in the U.S. decreased by 11.8% from 2001-2009.
- cardiac arrest
- cardiac outcomes
- cardiopulmonary resuscitation
- ventricular arrhythmia
- Therapeutic Hypothermia
- Received December 22, 2011.
- Accepted June 8, 2012.
- Copyright © 2012, American Heart Association, Inc. All rights reserved. Unauthorized use prohibited