Serum Lipids and Lipoproteins in Chinese Men and Women
Background—Due to rapid change in lifestyle risk factors, cardiovascular disease has become the leading cause of death in China. We aimed to estimate the national levels of serum lipids and lipoproteins among the Chinese adult population.
Methods and Results—We conducted a cross-sectional study in a nationally representative sample of 46,239 adults aged ≥20 years. Fasting serum total, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) cholesterol and triglycerides were measured using standard methods. The age-standardized estimates of total, HDL and LDL cholesterol, and triglycerides were 4.72 (95% confidence interval 4.70-4.73), 1.30 (1.29-1.30), 2.68 (2.67-2.70), and 1.57 (1.55-1.58) mmol/L, respectively, in the Chinese adult population. In addition, 22.5% (21.8-23.3) or 220.4 million (212.1-228.8) Chinese adults had borderline high total cholesterol (5.18-6.21 mmol/L) while 9.0% (8.5-9.5) or 88.1 million (83.4-92.8) had high total cholesterol (≥6.22 mmol/L). The population estimates for borderline high (3.37-4.13 mmol/L), high (4.14-4.91 mmol/L) and very high (≥4.92 mmol/L) LDL-cholesterol were 13.9% (13.3-14.5) or 133.5 million (127.0-140.1), 3.5% (3.3-3.8) or 33.8 million (31.2-36.5), and 3.0 (2.8-3.3) or 29.0 million (26.3-31.8) persons, respectively. In addition, 22.3% (21.6-23.1) or 214.9 million (207.0-222.8) persons had low HDL-cholesterol (<1.04 mmol/L). The awareness, treatment, and control of borderline high or high total cholesterol were 11.0%, 5.1%, and 2.8%, respectively, in the Chinese adult population.
Conclusions—Serum total and LDL cholesterol levels were high and increasing in the Chinese population. Without effective intervention, atherosclerotic cardiovascular diseases may soar in the near future in China.
- Received September 2, 2011.
- Accepted March 22, 2012.
- Copyright © 2012, American Heart Association, Inc. All rights reserved. Unauthorized use prohibited