Induced Septal Infarction/Nonsurgical Septal Reduction for Hypertrophic Obstructive Cardiomyopathy
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To the Editor:
Eugene Braunwald1 calls the new catheter interventional therapy for hypertrophic obstructive cardiomyopathy (HOCM) an ingenious approach with quite favorable results.
Braunwald states that we have reproduced the results obtained by Knight et al2 both with transient ischemia and ethanol-induced infarction and that Sigwart et al3 demonstrated in 1982 that brief occlusion of the septal artery with a balloon catheter causes transient reduction in the outflow pressure gradient. Knight et al2 state that Sigwart’s findings4 were confirmed by us.5
However, checking the papers and/or abstracts published by Sigwart, the opposite proves …