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Tissue Cations and Water in Arterial Hypertension
LOUIS TOBIAN, JOHN T. BINION
https://doi.org/10.1161/01.CIR.5.5.754
Circulation. 1952;5:754-758
Originally published May 1, 1952Jump to

Abstract
Human hypertensive subjects were found to have an increased sodium and water concentration in renal artery and psoas muscle. Hypertensive rats showed a high water content in their aortas. If the water and sodium content were increased in hypertensive arterioles as well as arteries, the swelling of the arteriolar walls would narrow the lumens enough to account for much of the increased peripheral resistance. Low sodium diets may alleviate hypertension by lowering the sodium and water contents in arteriolar walls toward normal values.
- © 1952 American Heart Association, Inc.
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- Tissue Cations and Water in Arterial HypertensionLOUIS TOBIAN and JOHN T. BINIONCirculation. 1952;5:754-758, originally published May 1, 1952https://doi.org/10.1161/01.CIR.5.5.754
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