Influence of Thyroidal Function on Vascular Reactivity in Dogs
Responsiveness to several vasoactive drugs has been found to be sharply reduced following suppression of thyroidal function with radioactive iodine, propylthiouracil or surgical thyroidectomy changed or increased with the appealance of the a thyroid state. Replacement therapy with desiccated thyroid did not restore vascular reactivity towards normal and produced inversion of adrenaline reesponses. Myxedema occurred in but 1 of 11 chronically athyroid dogs.
- © 1952 American Heart Association, Inc.