Pressor Substances in Arterial Hypertension
IV. Quantitative and Qualitative Studies of Pherentasin
Pherentasin is the only pressor substance found in blood of hypertensive patients which is not found in normal blood. This study defines its unit and compares its concentration with diastolic blood pressure level, type of hypertension, and age of patients. Lack of correlation between blood pressure level and pherentasin content suggests considerable variation in the amount of depressor substances in these patients. Chemical studies of pherentasin and its partial, tentative formula are discussed. Demonstration of the existence of an additional pressor fraction from blood which is volatile in alkaline solution is described.
- © 1952 American Heart Association, Inc.