Studies on Congestive Circulatory Failure
IV. The Effect of Various Diuretics on the Excretion of Water and Chlorides
Chloride balances were determined in 40 patients suffering from congestive circulatory failure and 6 with normal cardiac function, while diuretics were administered. The effect of digitalis was to increase the renal excretion of chlorides and water about equally; this action was significant in only one-third of the cases. Mercurial diuretics primarily increased the urinary concentration of chlorides in every case except when plasma chlorides were low. A xanthine (theobromine) appeared to exert a greater action on the excretion of water than on chlorides.
- © 1951 American Heart Association, Inc.