Serum triglycerides were determined for Oakland, Twin Cities, and Faribault participants as an ancillary study (for methods, cf. Chapter V). There was considerable variation in average per cent change from center to center and after different periods on diet. After 12 weeks in the First Study, average decreases occurred in all diet groups in the three centers. Those with higher baseline levels tended to show larger average decreases. Mean levels for each diet continued to fall between 12 and 28 weeks on assigned diet in Faribault and the Twin Cities, but returned to baseline in Oakland. Between 28 and 44 weeks triglyceride levels rose in all three centers; they were still well below baseline in Faribault and the Twin Cities, above baseline in Oakland. This variation in response from center to center over time is not easy to interpret. It may be related to inter-center differences in technical methods (cf. Chapter V). It is clear, however, that the main effect of the hypocholesterolemic diets was to lower serum triglycerides, particularly in men with elevated baseline levels.
- © 1968 American Heart Association, Inc.