Effect of Airway Hypocapnia on Mechanics of Breathing during Cardiopulmonary Bypass
Total cardiopulmonary bypass separates the lungs from the pulmonary arterial circulation. Continued ventilation with non CO2-containing mixtures during bypass will result in airway hypocapnia. Airway hypocapnia results in decreased compliance, increased work of breathing, and increased resistance to air flow. Reversal of airway hypocapnia increased compliance one-third, decreased work of breathing 20%, and decreased air flow resistance approximately 40% when compared to the values obtained during the period of low airway CO2. These changes in airway mechanics must be considered for pulmonary management during cardiac bypass.
- © 1967 American Heart Association, Inc.