The Effect of Digitoxin on Sodium Excretion, Creatinine Clearance and Apparent Cardiac Output
During the initial phase of decline in cardiac output following the administration of digitoxin to normal subjects, sodium excretion did not decline. Several days later, as cardiac output rose toward the normal level, sodium output decreased in most subjects. The possible implication of these re sults in relation to the regulation of sodium excretion is discussed.
- © 1951 American Heart Association, Inc.