Diagnosis of Diffuse Myocardial Fibrosis
Diffuse myocardial fibrosis is a disease of diverse etiology; the commonest cause is coronary artery disease. Physiologically, it produces a restriction of diastolic filling and thus resembles constrictive pericarditis and endocardial fibroelastosis. Clinically, it resembles constrictive pericarditis so closely that in many patients the differential diagnosis between these 2 disorders can be resolved only by thoracotomy and direct observation of the pericardium.
- © 1959 American Heart Association, Inc.