Effect of Potassium and of Desoxycorticosterone Acetate in Acute Heart Injury in the Rat
The rat myocardium was injured by means of a hot probe applied to the exposed surface of the left ventricle and the sequence of electrocardiographic changes was studied. Administered potassium as potassium chloride aggravated the electrocardiographic changes, while the administration of DCA improved the cardiographic picture. It is suggested that the beneficial action of DCA may be due to its plasma potassium lowering effect.
- © 1950 American Heart Association, Inc.