Effectiveness of an Oral, Nonmercurial Diuretic
Clinical Trial with Thirty-Five Patients
In a previous trial of aminometramid on 30 patients with peripheral edema, 19 became refractory to the drug. These 19 patients and another group of 16 with peripheral edema or ascites were placed on another nonmercurial diuretic aminoisometradine, which had shown promise in previous studies in animals and man. This group of 35 patients who had previously required frequent injections of mercurial diuretics were treated with the new diuretic for at least 8 months. Conclusions of this study are presented.
- © 1958 American Heart Association, Inc.