Measurement of Cardiac Output and Central Volume by a Modified Decholin Test of Circulation Time
A technic is described for determining mean circulation time, cardiac output, and central blood volume by use of graded dosages of sodium dehydrocholate (Decholin) administered into a peripheral vein. The indicator-dilution curves derived by the technic were compared with radiopotassium-dilution curves obtained simultaneously in 12 patients. The results showed a surprisingly good agreement between the 2 methods and indicate that the traditional Decholin test of circulation time can be modified to provide much more information than it has in the past.
- © 1957 American Heart Association, Inc.