Response by Weinberg et al to Letter Regarding Article, “Carotid Stent Fractures Are Not Associated With Adverse Events: Results From the ACT-1 Multicenter Randomized Trial (Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease)”
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Su and colleagues point to differences in the prevalence of previous carotid endarterectomy and severe carotid artery calcification between patients with and without carotid stent fracture.1 Because patients cannot be randomly assigned to fracture or no fracture, and because multiple baseline characteristics were reported, it is not unusual to observe nonrelevant differences between the groups that are most likely attributed to chance. Su et al suggest that we perform a multivariate logistic regression; however, given the low event rate, that may result in model …