Letter by Rahman and McEvoy Regarding Article, “Influence of Baseline Diastolic Blood Pressure on Effects of Intensive Compared With Standard Blood Pressure Control”
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To the Editor:
We read with interest the post hoc analysis by Beddhu and colleagues1 from SPRINT (Systolic Blood Pressure Intervention Trial). The authors demonstrated that the subgroup of SPRINT participants with baseline diastolic blood pressure (BP) <68 mm Hg benefited from intensive systolic BP lowering (target of 120 mm Hg) similar to those with higher baseline diastolic BP. This benefit was seen for both death and the primary composite end point of nonfatal myocardial infarction, acute coronary syndrome not resulting in myocardial infarction, stroke, acute decompensated heart failure, or cardiovascular death.
This excellent analysis …