Response by Magnussen et al to Letter Regarding Article, “Sex Differences and Similarities in Atrial Fibrillation Epidemiology, Risk Factors, and Mortality in Community Cohorts: Results From the BiomarCaRE Consortium (Biomarker for Cardiovascular Risk Assessment in Europe)”
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We thank Dr Wang for enriching the discussion on sex and mortality in individuals with atrial fibrillation (AF). As 1 of the first community studies that systematically addressed mortality risk in AF, the FHS (Framingham Heart Study) demonstrated an increased mortality in AF that was similar in women and men.1 This well-performed meta-analysis comprised >4 million individuals from a broad spectrum of studies in the majority samples with diseased individuals.2 Women and men with manifest AF usually differ by age, risk factor profile, and comorbidities. Therefore, differences in outcomes, including mortality, …