Response by Olde Engberink et al to Letter Regarding Article, “Use of a Single Baseline Versus Multiyear 24-Hour Urine Collection for Estimation of Long-Term Sodium Intake and Associated Cardiovascular and Renal Risk”

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In Response:
We thank Graudal and Mente for their interest in our article.1 We would like to clarify the authors’ comment that the confidence intervals indicate no outcome difference between baseline and follow-up measurements. The overlapping confidence intervals do not indicate absence of significance between both regression lines because they reflect confidence intervals that accompany the hazard ratios compared with a 2-g sodium intake. Moreover, we want to stress that both regression lines are based on the same dependent variable (ie, estimated sodium intake) and do not represent 2 different interventions. Therefore, these data seem to be a logical consequence of the large changes in sodium excretion …
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- Response by Olde Engberink et al to Letter Regarding Article, “Use of a Single Baseline Versus Multiyear 24-Hour Urine Collection for Estimation of Long-Term Sodium Intake and Associated Cardiovascular and Renal Risk”Rik H.G. Olde Engberink, Bert-Jan H. van den Born, Hessel Peters-Sengers and Liffert VogtCirculation. 2018;137:1538-1539, originally published April 2, 2018https://doi.org/10.1161/CIRCULATIONAHA.117.032710
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- Response by Olde Engberink et al to Letter Regarding Article, “Use of a Single Baseline Versus Multiyear 24-Hour Urine Collection for Estimation of Long-Term Sodium Intake and Associated Cardiovascular and Renal Risk”Rik H.G. Olde Engberink, Bert-Jan H. van den Born, Hessel Peters-Sengers and Liffert VogtCirculation. 2018;137:1538-1539, originally published April 2, 2018https://doi.org/10.1161/CIRCULATIONAHA.117.032710