Letter by Jordan and Biaggioni Regarding Article, “Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification”
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To the Editor:
The study by Li et al1 addressed a crucial public health issue. Air pollution has been recognized as an important cause of excess cardiovascular morbidity and mortality. Particulate matter appears to be particularly important in that regard. Yet much of the evidence is based on epidemiological surveys. Indeed, the mechanisms driving the increase in cardiovascular risk are poorly understood, and data from properly conducted trials testing preventive measures are scarce.
The investigators should be …