Abstract 14806: TV Viewing and Incident Venous Thromboembolism: the Atherosclerotic Risk in Communities Study
Introduction: TV viewing is associated with risk of arterial vascular diseases, but has not been evaluated in relation to venous thromboembolism VTE risk in a US. population.
Hypothesis: We tested the hypothesis that TV viewing very often is associated with an increased incidence rate of VTE independent of other VTE risk factors in a U.S. biracial cohort.
Methods: In 1987-1989, the Atherosclerosis Risk in Communities Study obtained information on the frequency of TV viewing in participants aged 45-64 and followed them prospectively. In individuals free of prebaseline VTE (n=15,158), we used a Cox proportional hazards models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of incident VTE according to frequency of television viewing (“Never or seldom”, “Sometimes”, “Often” or “Very often”). Information on TV viewing was updated in 1993-1995 and 2009-2011.
Results: During the 299,767 person-years of follow-up, we identified 691 VTE events. In a multivariable-adjusted model, the frequency of TV viewing showed a positive dose-response relation with VTE incidence (P for trend=0.036), in which “very often” viewing TV carried 1.71 (95% CI: 1.26-2.32) times the risk of VTE compared with “never or seldom” viewing TV. This association to some degree was mediated by obesity (25% mediation, 95% CI: 10.7-27.5). Similar associations were observed regardless of VTE subtype (unprovoked vs. provoked or pulmonary embolism vs. deep vein thrombosis). Even among individuals who met a recommended level of physical activity, viewing TV “very often” carried 1.80 (1.04-3.09) times the risk of VTE, compared to viewing TV “never or seldom”.
Conclusions: In this prospective population-based study, greater frequency of TV viewing was independently associated with increased risk of VTE, partially mediated by obesity. Achieving a recommended physical activity level did not eliminate the increased VTE risk associated with frequent TV viewing. Avoiding frequent TV viewing as well as increasing physical activity and controlling body weight might be beneficial for VTE prevention.
Author Disclosures: Y. Kubota: None. M. Cushman: None. N. Zakai: None. W.D. Rosamond: None. A.R. Folsom: None.
- © 2017 by American Heart Association, Inc.