Letter by Leggio et al Regarding Article, “Mediterranean Diet Improves High-Density Lipoprotein Function in High-Cardiovascular-Risk Individuals: A Randomized Controlled Trial”
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To the Editor:
Data from major cohort studies suggest that 82% of cardiovascular disease and 91% of diabetes mellitus risk may be prevented by changes in diet and lifestyle.1,2 In this context, we read with great interest the informative and well-conducted clinical study by Hernáez et al3 assessing the effects of an antioxidant-rich dietary pattern, such as a traditional Mediterranean diet, on high-density lipoprotein function in humans and demonstrating that this nutritional model, especially when enriched with virgin olive oil, improved high-density lipoprotein atheroprotective functions (cholesterol efflux capacity, cholesterol metabolism, antioxidant/anti-inflammatory properties, and vasoprotective effects) in humans. This article reports valuable …