Letter by Kotsiou and Gourgoulianis Regarding Article, “Pathophysiology of Takotsubo Syndrome”
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To the Editor:
We read with great interest the well-presented article titled “Pathophysiology of Takotsubo Syndrome” by Pelliccia et al1 reviewing the main characteristics of Takotsubo syndrome (TTS). Emotional factors most commonly play a key role in the triggering mechanisms of TTS. Until recently, TTS was thought to be typically provoked by negative stressors leading to the popular term “broken heart syndrome.”1 However, lately it has been shown that a positive life event can lead to TTS, and hence the recently proposed term “happy heart syndrome,”1,2 which constitutes 1.1% among all TTS cases.2 Four cases of TTS triggered by …