Correspondence
Response by Pérez de Isla et al to Letter Regarding Article, “Predicting Cardiovascular Events in Familial Hypercholesterolemia: The SAFEHEART Registry (Spanish Familial Hypercholesterolemia Cohort Study)”
Leopoldo Pérez de Isla, Adriana Saltijeral Cerezo, Pedro Mata
https://doi.org/10.1161/CIRCULATIONAHA.117.030993
Circulation. 2017;136:1984
Originally published November 13, 2017Leopoldo Pérez de Isla
Cardiology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos, Universidad Complutense, Madrid, Spain (L.P.d.I.).Fundación Hipercolesterolemia Familiar, Madrid, Spain (L.P.d.I., A.S.C., P.M.).
Adriana Saltijeral Cerezo
Fundación Hipercolesterolemia Familiar, Madrid, Spain (L.P.d.I., A.S.C., P.M.).Cardiology Department, Hospital del Tajo. Universidad Alfonso X el Sabio, Madrid, Spain (A.S.C.).
Pedro Mata
Fundación Hipercolesterolemia Familiar, Madrid, Spain (L.P.d.I., A.S.C., P.M.).

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In Response:
We thank Natale and colleagues for their interesting comments about our article.1 Their comments provide important information, and we would like to discuss several of these points.
We agree with the authors that familial hypercholesterolemia (FH) is frequent, underdiagnosed, and undertreated and that the …
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- Response by Pérez de Isla et al to Letter Regarding Article, “Predicting Cardiovascular Events in Familial Hypercholesterolemia: The SAFEHEART Registry (Spanish Familial Hypercholesterolemia Cohort Study)”Leopoldo Pérez de Isla, Adriana Saltijeral Cerezo and Pedro MataCirculation. 2017;136:1984, originally published November 13, 2017https://doi.org/10.1161/CIRCULATIONAHA.117.030993
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- Response by Pérez de Isla et al to Letter Regarding Article, “Predicting Cardiovascular Events in Familial Hypercholesterolemia: The SAFEHEART Registry (Spanish Familial Hypercholesterolemia Cohort Study)”Leopoldo Pérez de Isla, Adriana Saltijeral Cerezo and Pedro MataCirculation. 2017;136:1984, originally published November 13, 2017https://doi.org/10.1161/CIRCULATIONAHA.117.030993