Abstract P299: Resistance Exercise and Obesity Prevention
Introduction: Obesity is a significant cardiovascular disease (CVD) risk factor. There is still little evidence, however, on the effects of resistance exercise (RE), independent of and combined with aerobic exercise (AE), on the development of obesity.
Hypothesis: We hypothesised that RE, independent of AE, has significant benefits in obesity prevention.
Methods: Participants were 12,583 men and women aged 18 to 89 years (mean age, 47) who received a preventive medical examination during 1987-2005 in the Aerobics Center Longitudinal Study. Participants were free of CVD, cancer, and obesity at baseline. RE, AE, and meeting the 2008 US Physical Activity Guidelines (RE ≥2 days/week and AE ≥500 MET-minutes/week) were determined by self-reported leisure-time exercise. Obesity was defined as body mass index of ≥30 mg/kg2 using measured weight and height. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) of incident obesity by RE levels after adjusting for baseline age, sex, examination year, current smoking, heavy alcohol drinking, and meeting the AE guidelines.
Results: During an average follow-up of 5.6 years, 919 (7.3%) developed obesity. Individuals meeting the RE guidelines (26%) had a 20% lower risk of developing obesity (HR: 0.80; 95% CI: 0.68 to 0.94) after adjusting for potential confounders and meeting the AE guidelines. The HRs (95% CIs) of incident obesity were 0.80 (0.60-1.05), 0.68 (0.52-0.88), 0.92 (0.68-1.26), and 0.84 (0.62-1.13) in weekly RE time of 1-59, 60-119, 120-179, and ≥180 minutes/week, respectively, compared with no RE. We found similar results in both men and women. In the combined analysis of RE and AE, HRs (95% CIs) of incident obesity were 0.65 (0.46-0.92) in meeting RE guidelines only, 0.72 (0.62-0.83) in meeting AE guidelines only, and 0.61 (0.51-0.73) in meeting both RE and AE guidelines, compared to meeting none of the guidelines.
Conclusions: We found that RE, independent of and combined with AE, is associated with significantly lower risk of developing obesity, suggesting that RE should be added to habitual physical activity.
Author Disclosures: D. Lee: None. C. Lavie: None. X. Sui: None. S. Blair: None.
- © 2017 by American Heart Association, Inc.