Abstract P152: Cardiometabolic Risk Factors in Adolescent Blood Donors
Objective: Cardiometabolic risk factors have been extensively studied in adults, but to a lesser extent in adolescents. We assessed potential cardiometabolic risk factors in a large cohort of adolescent blood donors.
Methods: Glycated hemoglobin (HbA1c), blood pressure (BP), and total cholesterol were measured in 10,756 blood donors aged 16-19 years at school blood drives conducted by Carter BloodCare, a large North Texas blood center. Borderline values were defined as HbA1c 5.7-6.4%, BP (systolic/diastolic) 120-139/80-89 mm Hg, and total cholesterol 170-199 mg/dL. Elevated values were defined as HbA1c≥6.5%, BP ≥140/90, and total cholesterol ≥200 mg/dL. Subjects were classified into one of three subcohorts: (A) no borderline or elevated values (“healthy” subcohort); (B) one borderline value; (C) either two borderline values or one elevated value. The subcohorts were further stratified as shown in the Table.
Results: Of the 10,756 blood donors, 35.2% had one borderline cardiometabolic risk factor, and 17.9% had either two borderline or one elevated risk factor. There were more girls than boys in the “healthy” subcohort (p<0.0001). Girls had a higher prevalence of borderline or elevated total cholesterol (p<0.0001), whereas boys had higher prevalence of borderline or elevated BP (p<0.0001). Other differences between subcohorts are summarized in the Table.
Conclusion: More than half of adolescents in this study had at least one cardiometabolic risk factor that was either borderline or elevated. Blood donation programs can serve as highly efficient and cost-effective gateways for cardiometabolic risk screening in adolescents, with potential for the development of targeted interventions aimed at promoting healthy behaviors early in life, specifically among those at increased risk.
Author Disclosures: J. Keeton: None. S.J. Eason: None. M. Sayers: None. C. Ayers: None. M.O. Gore: None.
- © 2017 by American Heart Association, Inc.