Letter by Nadir Regarding Article, “Optical Coherence Tomography to Optimize Results of Percutaneous Coronary Intervention in Patients With Non-ST-Elevation Acute Coronary Syndrome: Results of the Multicenter, Randomized DOCTORS Study (Does Optical Coherence Tomography Optimize Results of Stenting)”
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To the Editor:
I read the article by Meneveau et al1 with great interest. The authors concluded that in patients with non-ST-elevation myocardial infarction, optical coherence tomography-guided percutaneous coronary intervention (PCI) is associated with higher postprocedure fractional flow reserve (FFR) than PCI guided by angiography alone without an increase in periprocedural complications.
Several concerns surround the use of FFR as a surrogate end point. The utility of FFR is firmly established in stable coronary artery disease but has been widely debated in patients with non-ST-elevation myocardial …