Letter by Fernandez-Jimenez et al Regarding Article, “Protective Effects of Ticagrelor on Myocardial Injury After Infarction”
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To the Editor:
We read with interest the article by Vilahur and colleagues.1 The authors should be congratulated for using the human-like pig model of ischemia/reperfusion to provide evidence that ticagrelor may limit myocardial injury (necrosis and edema formation), as measured by cardiac magnetic resonance (CMR).
Given that CMR can accurately identify myocardial areas with high water content, it has been widely used in the past years to retrospectively delineate the myocardium at risk (MaR). It is interesting to note that it has been assumed that the postischemia/reperfusion edematous reaction is stable for several days after myocardial infarction. On this basis, experimental …