Letter by Tsuda Regarding Article, “Prediabetes and Type 2 Diabetes Are Associated With Generalized Microvascular Dysfunction: The Maastricht Study”
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To the Editor:
I read with great interest the article by Sörensen and colleagues1 dealing with the microvascular dysfunction in subjects with prediabetes and type 2 diabetes mellitus. The results of their study demonstrated that retina and skin microvascular function determined by flicker light–induced retinal arteriolar dilatation and heat-induced skin hyperemia might be impaired in prediabetes with further deterioration in type 2 diabetes mellitus. In addition, the authors showed the inverse linear associations between measures of glycemia and microvascular function. These findings support the hypothesis that generalized …